Research Assistant in Ageing Biology (Epigenetics)

Research Assistant in Ageing Biology (Epigenetics)

We are looking for a highly motivated Research Assistant to join the Houseley lab at the Babraham Institute to work on epigenetic and metabolic dysregulation in ageing. This person will join our research programme aimed at suppressing ageing pathology by manipulating diet and metabolism, using yeast as a model system. By mutating proteins at the interphase between metabolism and epigenetics, we are altering the ageing trajectory of cells to improve health whilst maintaining typical cellular functions.

This exciting project will use cutting edge technologies to characterize the metabolic and epigenetic mechanisms that facilitate healthy ageing, providing unprecedented insights into the causes of maladaptive ageing. Techniques will include: general molecular biology, flow cytometry (spectral and imaging), generation and analysis of mRNA-sequencing libraries, mass spectrometry, CRISPR-based manipulations, yeast ageing and purification, among various other techniques.

The successful candidate must have a proficient understanding of molecular biology, and should be enthusiastic about ageing research. Success with this project also requires exceptional thoroughness, attention to detail, and excellent organizational skills. An interest in bioinformatic approaches for data analysis would be an advantage.

This post will also involve a laboratory management component to support the work of the Houseley group, including lab organisation, reagent and equipment purchasing, and Health and Safety oversight. This role reports to Dr Jon Houseley, a tenured group leader in the Epigenetics programme at the Babraham Institute.

Key areas of Responsibility

• Primary project involving the characterization of our healthy ageing yeast. This will include the design, implementation and interpretation of experiments. (70%)

• Lab management (organisation, purchasing, ordering, stock taking, administration) (20%)

• Health and Safety oversight which will include the completion of COSHH forms and working as the lab safety point person (10%)

This is a limited term appointment with funding for this post expected to be available for a period of 2 years.

For more information on the work of the group, please visit our website.

The Institute has joined the Technician Commitment initiative, which is a commitment to support the recognition, visibility, sustainability and career development of our research support community, which includes the BSU, Scientific Facilities, Computing, Stores & Purchasing, Technical Services, Health & Safety and the Research Assistant communities.

Closing date for applications is Monday, 14th August 2023.

However, we reserve the right to close the vacancy early depending on the volume of applications received.

The Babraham Institute welcomes applications from all sections of society.

NO AGENCIES PLEASE

The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute’s ambitions and attracts highly motivated and talented people. The Babraham Institute abides by the principles of the government’s Disability Confident Scheme and has a positive approach to employing disabled people.

Location: Babraham Institute, Cambridge

Department: Epigenetics

Contract type: Fixed Term Contract

Hours: 37

Salary: Starting salary is £30,628 per annum to £32,240 per annum (depending on experience)

REF-206 940