Computing Clinical Scientist
Location
Manchester, England, United Kingdom
Posted At
7/18/2025
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Description
Applications are invited for a motivated and skilled Computing Clinical Scientist to support the Real-World Evidence (RWE) research ambitions of the Manchester Cancer Research Centre (MCRC) within the Scientific Computing team of Radiotherapy Physics at The Christie NHS Foundation Trust.
The successful candidate will be responsible for developing and operating the research informatics infrastructure that underpins a pioneering programme of Real-World Evidence research, with a particular focus on the secure, ethical, and efficient use of anonymised clinical data. The role will involve close collaboration with clinical, research, and digital teams to expand the Trusted Research Environment (TRE), implement AI-based technologies such as Natural Language Processing (NLP), and integrate data quality profiling tools to enhance both research and clinical care pathways.
You will play a key role in optimising processes for rapid access to real-world data to support innovative clinical trials and ensure data quality across structured and complex datasets. The position offers opportunities to work with national and international partners, contribute to research publications, and support the implementation of novel analytics and decision support tools into clinical workflows. The post holder will have a computing-related specialism (e.g. Clinical Scientific Computing, Clinical Informatics) or medical physics with experience in computing and will ideally be HCPC registered.
Scientific Computing Support
The successful candidate will aid the team in delivering scientific computing solutions for a range of radiotherapy physics projects. This will include supporting other members of the physics team in their computing work. They will be responsible for pushing the development of the research informatics infrastructure from The Christie in collaboration with the Manchester Cancer Research Centre.
Radiotherapy Systems And Data Management
The post holder will ensure all work complies with relevant UK legislation and standards (e.g., IRR 2017, IRMER 2017, MDR, GDPR). They will optimise processes for rapid, secure access to real-world data and support the integration and governance of data flows with regional and national Secure Data Environments (SDEs).
Clinical Implementation and Evaluation
The candidate will facilitate the implementation of novel analytics and AI-based decision support tools into the clinical workflow. They will develop strategies for embedded evaluation of new clinical technologies.
Supervision
The role includes supervision of trainee clinical scientists and dosimetrists, as well as prioritising and managing a diverse range of scientific computing projects with varying complexity.
Research & Development
The successful candidate will support hypothesis-generating and clinically relevant discovery research using large retrospective patient cohorts. They will contribute to research proposals, funding applications, and publications.
The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country.
We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years.
We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.
For further details / informal visits contact: Name: Samuel Ingram Job title: Radiotherapy Scientific Computing Lead Email address: [email protected] Telephone number: 01610 918 7591
Matthew Clarke - Radiotherapy Physics Group Leader [email protected] on 0161 918 7180
The successful candidate will be responsible for developing and operating the research informatics infrastructure that underpins a pioneering programme of Real-World Evidence research, with a particular focus on the secure, ethical, and efficient use of anonymised clinical data. The role will involve close collaboration with clinical, research, and digital teams to expand the Trusted Research Environment (TRE), implement AI-based technologies such as Natural Language Processing (NLP), and integrate data quality profiling tools to enhance both research and clinical care pathways.
You will play a key role in optimising processes for rapid access to real-world data to support innovative clinical trials and ensure data quality across structured and complex datasets. The position offers opportunities to work with national and international partners, contribute to research publications, and support the implementation of novel analytics and decision support tools into clinical workflows. The post holder will have a computing-related specialism (e.g. Clinical Scientific Computing, Clinical Informatics) or medical physics with experience in computing and will ideally be HCPC registered.
Scientific Computing Support
The successful candidate will aid the team in delivering scientific computing solutions for a range of radiotherapy physics projects. This will include supporting other members of the physics team in their computing work. They will be responsible for pushing the development of the research informatics infrastructure from The Christie in collaboration with the Manchester Cancer Research Centre.
Radiotherapy Systems And Data Management
The post holder will ensure all work complies with relevant UK legislation and standards (e.g., IRR 2017, IRMER 2017, MDR, GDPR). They will optimise processes for rapid, secure access to real-world data and support the integration and governance of data flows with regional and national Secure Data Environments (SDEs).
Clinical Implementation and Evaluation
The candidate will facilitate the implementation of novel analytics and AI-based decision support tools into the clinical workflow. They will develop strategies for embedded evaluation of new clinical technologies.
Supervision
The role includes supervision of trainee clinical scientists and dosimetrists, as well as prioritising and managing a diverse range of scientific computing projects with varying complexity.
Research & Development
The successful candidate will support hypothesis-generating and clinically relevant discovery research using large retrospective patient cohorts. They will contribute to research proposals, funding applications, and publications.
The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country.
We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years.
We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.
For further details / informal visits contact: Name: Samuel Ingram Job title: Radiotherapy Scientific Computing Lead Email address: [email protected] Telephone number: 01610 918 7591
Matthew Clarke - Radiotherapy Physics Group Leader [email protected] on 0161 918 7180
Advertise with us by contacting: [email protected]
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