IT/OT Systems Engineer, GxP Manufacturing and Labs

Oxford, England, United Kingdom

6/26/2025

The Role

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases.

As an employee, you'll be part of a continually growing organization, working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives.

Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience, with the potential to make a significant impact on patients' lives worldwide.

Moderna's mission is to establish a leading-edge research, development, and manufacturing facility at Harwell, as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic, NHS and government partners across the UK. We're looking for global experts eager to join us in this endeavour, contributing to a future where access to life-saving vaccines is a reality for all.

We are looking for a technically versatile IT/OT Systems Engineer who can operate with equal effectiveness in server rooms, on the manufacturing floor, or in discussions with digital teams. This individual will support and maintain both the infrastructure and applications used in our manufacturing environment, ensuring seamless operations that adhere to GMP standards. This position is ideal for a highly skilled engineer who thrives at the intersection of IT and OT, switching between systems-level problem-solving and on-the-ground operational support. You will collaborate closely with automation engineers, lab engineers, plant and operations teams, and the broader digital network, providing vital support across a range of technologies. This is a unique opportunity to support critical manufacturing and lab platforms, while gaining exposure to cutting-edge technologies and global operations. You will also play a key role in integrating and securing digital platforms, aligning with modern manufacturing strategies, and supporting innovation initiatives, including proximity to Generative AI-enabled tools.

Here’s What You’ll Do

Your key responsibilities will be:

• Ensure uninterrupted performance of systems that support GMP operations, including virtual machines, servers, and critical manufacturing applications.
• Troubleshoot and maintain infrastructure components such as VMware, Windows Servers, DNS/DHCP, network architecture, and wireless networks in GMP settings.
• Administer and support core manufacturing systems like Syncade, DeltaV, OSI PI, BMS, ThinManager, and various analytical instruments and label printers.
• Collaborate with cybersecurity and enterprise digital teams to address compliance, security, and systems integration requirements.
• Develop and maintain disaster recovery and business continuity plans specific to manufacturing and lab environments.
  
  

Your Responsibilities Will Also Include

• Partnering with scientists, engineers, and operators to design and implement scalable, efficient IT/OT systems and define Service Level Agreements (SLAs).
• Participating in digital initiatives that aim to tightly integrate IT/OT capabilities with research, manufacturing, and analytical science environments.
• Supporting qualification and validation processes (IQ/OQ/PQ) in line with regulatory GxP frameworks.
• Providing strategic input to stakeholders on IT/OT tools and infrastructure necessary to meet evolving operational demands.
• Actively contributing to the implementation and troubleshooting of cybersecurity applications, as well as network topology optimization for lab and plant systems.
  
  

The key Moderna Mindsets you’ll need to succeed in the role:

• We digitize everywhere possible using the power of code to maximize our impact on patients. You will be at the center of integrating digital tools with physical infrastructure—automating, optimizing, and scaling operations that ultimately improve healthcare delivery.
• We behave like owners. The solutions we’re building go beyond any job description. Your ability to operate autonomously across complex systems and engage proactively with both local and global teams will be essential in delivering reliable, compliant, and impactful digital infrastructure across our operations.
  
  

Here’s What You’ll Need (Basic Qualifications)

• Bachelor’s degree in Computer Science, Information Technology, Industrial Engineering, physical science or related field or relevant experience
• 6+ years of experience working with IT/OT infrastructure in manufacturing, lab systems, control systems and building management systems
• Experience with IT/OT implementation with DCS, MES, BMS, PLC, OPC, HPLC, GC, LIMs, lab analyzers
• Prior experience working for a Pharmaceutical company required
• Experience working with virtual environment (VMware/Hyper-V) and/or cloud platform (AWS preferred)
• Experience working with RDBMS (SQL Server or Oracle)
• Experience working with application and web server (IIS)
• Experience working with backup/recovery systems (Acronis, Veeam, N2WS, etc.)
• Experience working with Cybersecurity endpoint protection applications (Crowdstrike, Symantec, McAfee, Carbon Black, etc.)
• Experience working with infrastructure tools (Dynatrace, Pager Duty, Splunk)
• Understanding of network routing, switching and firewall concepts
  
  

Here’s What You’ll Bring to the Table (Preferred Qualifications):

• Creative, analytical, and strong problem-solving skills and a whatever it takes’ attitude
• Ability to liaison between IT, Automation, Engineering, Manufacturing, QC, and QA teams
• Work independently, with limited direction, to achieve expected results
• Adapt well under pressure to any given situation that may arise, in a professional manner and with positive results, in support of a multi-location, 24x7 environment
• Take the initiative to drive and effect change in a dynamic, high standards environment while maintaining a positive approach with management and peers
• Operates with a highly collaborative work style, and possess strong interpersonal skills with the ability to build successful professional working relationships
• Work effectively in a cross-functional, fast-paced project environment
• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative
• As part of Moderna’s commitment to workplace safety, this role may require an enhanced pre-employment check.
  
  

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our global benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Quality healthcare and insurance benefits
• Lifestyle Spending Accounts to create your own pathway to well-being
• Free premium access to fitness, nutrition, and mindfulness classes
• Family planning and adoption benefits
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments
• Location-specific perks and extras!
  
  

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is committed to equal opportunity in employment and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at [email protected].