Laboratory Research Scientist

Laboratory Research Scientist

Details of the role:

Working pattern: Monday – Friday. This is a full-time, fixed term (12 months maternity cover) position on Crick terms and conditions of employment.

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

The Research Group

We are looking for an enthusiastic and proactive person to provide research support to our team at the Francis Crick Institute. Our group is studying protein ubiquitination, a post-translational modification that regulates virtually every aspect of cellular life. Specifically, we are interested in the protein machinery and regulatory mechanisms mediating the ubiquitination process.

To gain molecular insight into this process we are employing a broad array of structural, biochemical and biophysical approaches. In parallel, we’re applying chemical biology approaches to develop chemical probes and inhibitors targeting ubiquitin system components.

About the role

We are looking for a Laboratory Research Scientist who will join our team and support the structural and functional studies we are carrying out on different components of the ubiquitin system.

In this role, you will have the opportunity to be involved in developing tools that support ongoing projects in the team, working closely with other lab members. You should have previous experience in general molecular biology techniques and protein expression and purification methods, though specific training can be provided as required. You will carry out a variety of biochemical assays and will be involved in novel assay development as the need arises.

If you have previous lab experience as well as a B.Sc. or M.Sc. in biochemistry or related discipline, this may be a great opportunity for you to join the team.

Please see the full job description here.

Click on this link to see more information about the lab.

What you will be doing

As a Laboratory Research Scientist at the Crick, some of your key responsibilities will include:

• Provide technical and research support in the area of protein biochemistry and molecular biology, including production of recombinant proteins for structural studies
• Contribute to the development of biochemical assays to study protein ubiquitination
• Provide support to establish novel technologies in the lab

About you

You will have:

• B.Sc. or M.Sc. in biochemistry or related discipline
• Proven working knowledge and experience in general molecular biology techniques and recombinant protein production
• Experience in the use of eukaryotic systems for recombinant protein production
• Good technical and problem-solving skills
• Ability to plan and manage your own work schedule and maintain accurate records to document research progress
• Ability to use Windows operating system (e.g. Access, Excel, Word) and Web browser-based databases.
• Strong collaborative ability and teamwork experience

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.
• We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: [email protected]

Find out more about life at the Crick.

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
• Health & Well-being:
• 24/7 GP consultation services.
• Occupational health services and mental health support programs.
• Eye care vouchers and discounted healthcare plans.
• Work-Life Balance:
• Back-up care for dependents.
• Childcare support allowance.
• Annual leave purchase options.
• Crick Networks offering diverse groups’ support, community and inclusive social events.
• Perks:
• Discounted gym memberships, bike-to-work scheme, and shopping discounts.
• Subsidised on-site restaurant and social spaces for team interaction.

Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.

We reserve the right to withdraw this advert at any given time due to the number of applications received.