Postdoctoral Fellow - Findlay Lab

Postdoctoral Fellow – G. Findlay lab

Reporting to: Greg Findlay, Group Leader

Contact term: This is a full-time fixed term (4 year) position on Crick terms and conditions of employment.

Salary for this Role: From £45,500 with benefits, subject to skills and experience

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

The Francis Crick Institute’s Genome Function Laboratory’s mission is to develop and deploy powerful genome editing tools to explore how genetic variants impact biological function. By systematically dissecting the mechanisms underlying human genotype-phenotype relationships, the lab’s work promises to advance the application of human genomics.

The Findlay lab was established in 2020, and currently is home to 2 postdocs, 4 PhD students and 1 staff research scientist. The lab and the Crick are highly committed to maintaining a supportive research environment, and strongly value collegiality and sharing of expertise.

As a Postdoctoral Fellow in the Findlay lab, you will lead independent research projects with considerable autonomy to influence the course of the science, whilst benefiting highly from the collaborative environment of the lab.

This is a great opportunity for you to develop in your research skills and make major contributions to the field of functional genomics.

If you have expertise in functional genomics, biotechnology, computational biology, or a related area of research, and are passionate about technology development and the generation of large-scale experimental data, we would love to hear from you!

See the full job description here.

See here for more information about the lab.

What you will be doing

Multiple post-doctoral projects are available depending your area of interest. We are keen to better understand how variants in the human non-coding genome lead to disease phenotypes by studying fundamental mechanisms of gene regulation. In this broad area, potential projects include:

• Developing new multiplex assays to study effects of variants on gene regulation
• Developing strategies to record complex molecular phenotypes to DNA
• Employing prime editing to produce massive data sets designed to advance computational models to predict gene expression
• Revealing new mechanisms of genetic disease by assaying large sets of variants prioritised from human cohorts, leveraging databases such as Genomics England

About you

You will have:

(Minimum criteria *)

• PhD awarded or in the final stages of PhD submission *
• Strong track record of scientific contribution, as evidenced by publications, preprints, or submitted manuscripts *
• Expertise in bioinformatics, human genomics, or analysis of high-throughput data *
• Deep knowledge of molecular biology *
• Ability to clearly document work and communicate results effectively
• Ability to work efficiently as part of a team

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.
• We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: [email protected]

Find out more about life at the Crick.

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

• Visas: Applicants for this role will be eligible for sponsorship to work in the UK
• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
• Health & Well-being:
• 24/7 GP consultation services.
• Occupational health services and mental health support programs.
• Eye care vouchers and discounted healthcare plans.
• Work-Life Balance:
• Back-up care for dependents.
• Childcare support allowance.
• Annual leave purchase options.
• Crick Networks offering diverse groups’ support, community and inclusive social events.
• Perks:
• Discounted gym memberships, bike-to-work scheme, and shopping discounts.
• Subsidised on-site restaurant and social spaces for team interaction.
• Career support: A Post-doc to PI programme and other career development activities

Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.

We reserve the right to withdraw this advert at any given time due to the number of applications received.