Job Description
Grade UE07: £41,064- £48,822 per annum
CMVM- Centre for Cancer Research, School of Genetics and Cancer
Full Time: 35 hours per week
Fixed Term: 12 months
The Opportunity
We are looking for a Post-Doctoral Research Assistant to join our team based at IGC (ECRC) for a one year post. Our lab studies mutations in the metabolic isocitrate dehydrogenase (IDH1/2) genes and this project focusses on how these mutations re-program liver cells, in the context of biliary cancer. We are using CRISPR-edited human cells and novel transgenic models in mice to examine how these mutations affect the liver’s response to damage and explore the link between injury and metabolic re-programming.
Ideally, the post holder should have experience of animal work, cell culture, tissue processing and will be able to perform laboratory analyses of human and mouse tissue including genotyping, IHC, rt-PCR, western blotting and prepare samples for external providers (transcriptomics, metabolomics). A large proportion of the work will be based on animal experiments; a PIL is a desired but not an essential requirement for the post. Experience of in vivo models of liver cancer and/or liver disease would be highly desirable.
This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
The salary for this post is
£41,064 to £48,822 per annum.
Your Skills And Attributes For Success
- A proactive, enthusiastic approach to science
- Ability to work both independently and as part of a team
- Experience of molecular techniques that may include (but not limited to) rt-PCR, IHC, genotyping and sample preparation for external providers
- Experience of tissue processing and cell culture
Click here to view a copy of the full job description (opens new browser tab).
Application Information
Please ensure you include the following documents in your application:
As a valued member of our team you can expect:
- A competitive salary
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community
- Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits
Championing equality, diversity and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our
right to work webpages (opens new browser tab)
The University may be able to sponsor the employment of international workers in this role. This will depend on a number of factors specific to the successful applicant.
Key dates to note
The closing date for applications is
12 December 2025.
Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.
About Us
As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.
About The Team
The School of Genetics and Cancer is one of the six Schools that make up the College of Medicine and Veterinary Medicine (CMVM). The School is home to the Institute of Genetics and Cancer (IGC) whose goals are to carry out excellent genetic, genomic, cellular and clinical science, so that we contribute significantly to the understanding of human development, physiology and disease, and apply this knowledge for the benefit of patients and society. The IGC is one of the College’s five world-leading research institutes. The teams in the six CMVM Schools work together to build outstanding discovery and translational research programmes designed to answer the major challenges facing humanity, animal and planetary health, now and in the future. The College’s undergraduate and postgraduate teaching is delivered through Edinburgh Medical School and the Royal (Dick) School of Medical Studies with contributions from all six schools.
To find out more visit: School of Genetics and Cancer webpage ( https://medicine-vet-medicine.ed.ac.uk/school-of-genetics-and-cancer ) (opens a new browser tab).
