Job Description
Grade UE07: £41,064 - £48,822 per annum pro-rata if part-time
College of Medicine and Veterinary Medicine / Clinical Sciences / Institute for Regeneration and Repair / Centre for Inflammation Research
Full-time: 35 hours per week
Fixed-term: for 2 years
We are looking for a
Postdoctoral Research Fellow studying renal senescence and fibrosis signalling using in vitro and in vivo models of aging and disease. The post will be based in the Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh with Professor David Ferenbach.
This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.
The Opportunity
This fellowship forms part of a MRC-funded Senior Clinical Fellowship, based in the Institute for Regeneration and Repair – home to over 1000 research staff and students. Its focus is on the identification of novel pathways linking senescent epithelia to tissue fibrosis in human chronic kidney disease. The post holder will lead the validation of these pathways using advanced cell culture approaches to interrogate the interactions between healthy and senescent renal epithelia and renal leukocytes and fibroblasts. Further work will explore the potential for these pathways to be targeted in vivo to promote senescent cell clearance and prevent senescent cell accumulation with ageing and tissue injury.
Your Skills And Attributes For Success
- PhD or equivalent (or will be shortly awarded a PhD) in biological sciences.
- Experience of in vivo work, ideally including models of renal injury and fibrosis.
- Experience of in vitro work, ideally working with models of epithelial cell culture ± co-culture.
- Experience of a several biological assays for determining mechanisms, e.g., several of: histology, light or fluorescent microscopy, absorbance assays, ELISA, flow cytometry, DNA/RNA extraction, qPCR.
Click to view a copy of the full job description (opens new browser tab).
As a valued member of our team you can expect:
- A competitive salary.
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community.
- Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.
Championing equality, diversity and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our
right to work webpages (opens new browser tab).
The University may be able to sponsor the employment of international workers in this role. This will depend on a number of factors specific to the successful applicant.
Please note if the role is offered on a part-time basis, it may result in sponsorship being dependent on a number of factors specific to the successful applicant or the role no longer meeting the Home Office’s criteria for sponsorship.
Key notes for applicants
As part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV.
The closing date for applications is
3 rd September 2025.
Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.
We anticipate that interviews will be held within 2-3 weeks of the advert closing date.
About Us
As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.
About The Team
IRR (Director: Prof Stuart Forbes)has a 5-year income of over £200M and supports over 800 staff and 200 students within a collaborative hub for commercial, clinical and academic endeavour. We are based on the Edinburgh Bioquarter campus. Our three main centres are the Centre for Reproductive Health (CRH), the Centre for Regenerative Medicine (CRM), and the Centre for Inflammation Research (CIR). Bringing together world leading research expertise to drive understanding and deliver clinical and translational outcomes. IRR contains staff and students from two colleges (CMVM and CSE) and 4 Schools add to the complexity of the role.
IRR has a work environment built on trust and encourages the very best talent from all backgrounds and at all levels to join us as a diverse team strengthens our ability to innovate and support the cutting-edge world leading research we aspire to. We collaborate widely to advance understanding and knowledge as outlined in the University’s Strategy 2030. Employees and students are supported and empowered to build, shape and inform aspects of our culture in areas such as sustainability, mental health and wellbeing. Our team is ambitious, acts with integrity and demonstrates commitment to progress and impact.
In aiming to be an accessible employer and creating an inclusive environment, we encourage applicants who wish to work flexibly (including part-time, condensed hours and other forms). https://www.ed.ac.uk/regeneration-repair
