Postdoctoral Research Scientist (Signalling)

We are seeking an enthusiastic and talented Postdoctoral Research Scientist to join the David group at the Babraham Institute in Cambridge. Our overarching goal is to discover mechanisms that promote healthy ageing and alleviate age-related diseases such as Alzheimer’s disease. Our group has uncovered mechanisms that prevent age-related protein aggregation, a major contributor to functional decline. Notably, we discovered a proteostasis network that safeguards proteins from aggregation in the extracellular space in C. elegans (PMID: 32641833). Our group is embedded within the Signalling Programme, which offers a vibrant, collaborative environment and access to world-class facilities.

In this role, you will have the opportunity to develop an independent research project investigating mechanisms of protein quality control in the extracellular space. Your work will combine in vitro assays to characterize protein aggregation and in vivo studies in C. elegans using imaging, proteomics, and functional assays to explore how extracellular proteostasis influences organismal health. This position is ideal for a curiosity-driven scientist who thrives on tackling challenging questions and pushing the boundaries of knowledge. Applicants should hold a PhD in biochemistry, cellular or molecular biology, or a related discipline, and demonstrate a strong track record in academic research. Prior experience in molecular cloning and biochemical techniques, including protein purification and western blotting, is essential. Additional expertise in microscopy, cell culture and proteomics is highly desirable, and familiarity with C. elegans research would be advantageous, although not required.

The Babraham Institute is a charity, world renowned for its research in life sciences to enhance lives and improve wellbeing. Postdocs have access to excellent career development courses in the Postdoc Academy (University of Cambridge) and high-quality scientific training is offered by the different core facilities at the Babraham Institute.

Funding for this position is initially available for three years. A full job specification and role requirements can be found attached to this vacancy on our website.

The closing date is Monday, 5th January 2026.

Applicants must hold a PhD or have their thesis submitted when commencing the post. Please note that you will be appointed on the starting salary of £34,500 per annum, if you have not yet been awarded your PhD.

NO AGENCIES PLEASE

The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute’s ambitions and attracts highly motivated and talented people. The Babraham Institute is a Disability Confident Employer and has a positive approach to employing disabled people.

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