Process R&D Scientist II (Upstream)

Oxford, England, United Kingdom

7/22/2025

Location:

Oxford, GB

Company: oxfordbiom

Join Us in Changing Lives.

At OXB, our people are at the heart of everything we do. We’re on a mission to enable life-changing therapies to reach patients around the world—and we’re looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.

We are currently recruiting for a Scientist ll PRD (Upstream) to join the team. The purpose of this role is to perform and report laboratory-based experiments or investigations, in accordance with scientific or regulatory requirements, and in line with departmental objectives.

Oxford Biomedica’s Process R&D team consists of experienced scientists and engineers that have extensive expertise in all aspects of upstream and downstream development. PR&D take processes from the laboratory “bench” scale and apply process expertise and engineering fundamentals for delivery to Manufacturing.

Your responsibilities in this role would be:

• Perform routine suspension cell culture activities to support viral vector production within the Process R&D group.
• Develop and optimize platform upstream cell culture processes for producing lentiviral vectors, working within small project teams in the Process R&D group.
• Design and execute small scale and laboratory scale bioreactor cell culture activities for scale-up/scale-down of existing bioprocesses.
• Support new product process development and scale-up activities for viral vector production in GMP.
• Involvement in activities ranging from viral vector production, process optimization, technology transfer, and process validation activities associated with the manufacture of new gene therapy vectors.
• Lead the execution of experiments /investigations in accordance with correct methodologies and procedures, under the direction of a Team Leader or senior scientist.
  
  

We are looking for:

• Minimum BSc Degree programme level.
• Postgraduate degree and/or relevant experience working with viral vectors is desirable.
• A sound understanding and/or experience of basic mammalian suspension cell culture principles and processes.
• Someone who is innovative, shows initiative, and is collaborative.
• Demonstrates good time management skills to be able to effectively manage their own workload.
• Fluency in written and spoken English, with good presentation skills.
  
  

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us?

• 💸 Competitive total reward packages
• 🧘 Wellbeing programmes that support your mental and physical health
• 🚀 Career development opportunities to help you grow and thrive
• 🤝 Supportive, inclusive, and collaborative culture
• 🧪 State-of-the-art labs and manufacturing facilities
• 🌍 A company that lives its values: Responsible, Responsive, Resilient, Respect
  
  

We want you to feel inspired every day. At OXB, we’re future-focused and growing fast. We succeed together—through passion, commitment, and teamwork.

Ready to Make a Difference?

Collaborate. Contribute. Change lives.