Research Assistant in T cell Immunology / Immunotherapeutics

Research Assistant in T cell Immunology / Immunotherapeutics

Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, John Radcliffe Hospital, Headington, Oxford

This is an exciting and unique opportunity for a talented, curious scientist who wants to make new scientific discoveries in T cell immunology and immunotherapeutics. You will work in the Vyas Laboratory on discovering new peptide-HLA-II (pHLA-II) antigens and their cognate T cell receptors (TCRs), interrogating their function, molecular and biophysical features and conduct proof of concept work to establish their utility as immunotherapeutics.

You will be part of a multi-disciplinary team that includes immunologists with molecular, cellular, biochemical and structural expertise. You will work with patient samples and dissect alloreactive immune responses, repurposing them to make novel TCR-T cell and soluble bispecific T cell engager therapeutics.

You will have an undergraduate degree in a relevant biological science, together with relevant laboratory and computational experience (flow cytometry, cell culture, molecular sub-cloning and analysis of next generation sequence data). Experience in coding and using computational pipelines with specialist knowledge in T cell immunology and immunology of cancer and cancer immunotherapeutics will be essential.

The role could suit an applicant wanting to go onto do a PhD or wanting to explore working in the Vyas Laboratory on a longer term basis.

The post is available fixed-term for 12 months, funded by Yellowstone Bioscience.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12:00 noon on Monday 15 July 2025. Interviews will be held w/c 28 July 2025.