RWE & Medical Affairs Commercial Lead

Ampersand Health is building the world’s first agentic hospital for long-term inflammatory conditions. We specialise in digital therapies and data-driven care for people living with immune-mediated diseases like Crohn’s, Colitis, Rheumatoid Arthritis, and Psoriasis. Our vision is a future in which patients benefit from personalised medicine and precision care, powered by AI and real-world data.

Founded by doctors and patients, we partner with the NHS, charities and pharmaceutical companies to support people from diagnosis to sustained remission, enabling smarter, more efficient care. Our platform combines behavioural science, clinical expertise, and AI-driven prediction models to improve health outcomes and quality of life.

Ampersand is an alumnus of prestigious accelerators, including PWC Scale Health, Pharmstars and the NHS Innovation Accelerator, recognised in the Digital Health Global 100, and has won awards from Innovate UK, the HSJ, NHSX, and others. We’re proud to be a mission-driven, evidence-based UK company with a growing presence in the US and other international markets.

We’re looking for a senior, commercially minded RWE & Medical Affairs Commercial Lead to own and scale Ampersand Health’s pharma-facing propositions across Real World Evidence, Medical Affairs, and evidence-led digital innovation.

This is a hands-on role responsible for converting Ampersand’s unique assets, including longitudinal patient data, behavioural insights, disease-specific content, and predictive analytics, into clearly scoped, high-value collaborations with pharmaceutical companies.

You will work closely with senior stakeholders across Medical Affairs, RWE, HEOR, and Digital Innovation teams, shaping propositions that address real clinical and strategic questions while maintaining scientific credibility and operational rigour.

Commercial Development & Prospecting

• Own the commercial development of Ampersand’s RWE and Medical Affairs propositions, from early prospecting through to contract execution.
• Lead outbound engagement with pharmaceutical companies, prioritising Medical Affairs, RWE, and evidence-generation buyers across large pharma and mid-cap immunology biotech.

Proposition Design & Delivery Oversight

• Work with internal clinical, data science, and product teams to shape evidence-led propositions, including patient journey and disease burden studies, post-marketing and observational RWE programmes, and insight generation to support launch planning, optimisation, and lifecycle management.
• Ensure that propositions are scientifically credible, operationally feasible, and commercially sound.
• Provide senior oversight during delivery to maintain alignment with agreed objectives and customer expectations.

Stakeholder Management

• Act as the primary commercial interface for pharma partners once opportunities are qualified.
• Build trusted, long-term relationships with senior Medical Affairs and RWE stakeholders.

Internal Collaboration & Strategy

• Work closely with the CEO, clinical leadership, and product teams to refine Ampersand’s RWE and Medical Affairs strategy.
• Feed market intelligence and customer feedback into product roadmap and data strategy discussions.
• Contribute to the development of repeatable commercial playbooks and standardised propositions over time.

• You want to be doing work that sits at the intersection of science, medicine, and real-world impact.
• You are commercially astute but comfortable operating in medically led environments, with a strong appreciation for evidence standards and governance.
• You are confident engaging senior pharma stakeholders and translating complex concepts into clear, structured propositions.
• You are pragmatic, organised, and able to move opportunities forward without over-engineering.

Must-Have

• Significant experience working with pharmaceutical companies in Medical Affairs, RWE, HEOR, or closely related commercial roles.
• A strong understanding of how real-world data and evidence are used across the product lifecycle.
• Proven ability to originate, scope, and close complex, evidence-led commercial engagements.
• Excellent written and verbal communication skills, with the ability to engage scientific and non-scientific audiences.
• Comfort operating in regulated, evidence-driven environments.

Nice-to-Have

• Experience in immunology, inflammation, or long-term conditions.
• Background in digital health, analytics, or data-enabled services.
• Existing network across Medical Affairs or RWE teams in Europe or the US.
• Experience working with early-stage or scaling health technology companies.
  

We are a dynamic high-growth company in the digital health space, with a team who are all-in on our purpose. You’ll be joining a group of motivated people working to improve the health and quality of life of people living with complex long-term conditions.

In addition, we offer:

• Employee share option scheme
• Hybrid, flexible working patterns
• 9 day fortnights
• Company pension scheme
• 24 days annual leave