We have a vacancy for a Senior Scientist to join the Bioassay team at our Cambridge (UK) site. In this primarily lab-based role you will be working as part of the Bioassay group on client-facing projects, and will have the opportunity to learn new techniques in a fast-paced but supportive environment.
Candidates will be expected to demonstrate experience in bioassays, with an emphasis on relative potency assays. Expertise in assay development and qualification/validation is essential, including experience with design of experiments (e.g. using JMP or equivalent), and knowledge of required statistics and regulatory guidelines.
Abzena provides the most complete set of solutions in integrated early discovery to mid-phase biotherapeutic and ADC drug development services in the pharmaceutical industry. Working with companies and academic groups all over the world, Abzena supports the development and manufacture of better treatments for patients. Multiple antibodies which have been created using Abzena’s technologies are currently being progressed through clinical development by our partners.
Situated on an attractive parkland estate, in a spacious, beautifully landscaped setting, the Abzena building on the Babraham Research Campus, Cambridge has been purpose-built to accommodate Abzena’s needs and enables all the Group’s UK-based science teams to work together in a single, state-of-the-art facility.
Responsibilities
- To design and carry out routine and complex experiments as necessary
- To perform complex/novel techniques under supervision
- To manage own work schedule to ensure tasks are met within the expected timeframe
- To analyse and interpret your own data
- To be responsible for the quality of your own work
- To prepare data for, contribute to the drafting of reports and presentations
- To contribute to internal and client meetings
- To draft and contribute to Quality and Controlled documents
- To undertake any other duties relevant to the position and level
Qualifications
- BSc or MSc with a minimum of 3 years relevant experience in bioassay development and qualification/validation.
- Relevant laboratory experience, maintaining and passaging cell lines, and setting up biochemical (e.g. ELISA) and cell-based assays (e.g. proliferation, cytotoxicity, reporter) using fluorescence or luminescence plate-based methods.
- Demonstrated skills in MoA-based assay design and development using a DoE approach (e.g. use of JMP or equivalent), good troubleshooting skills.
- Strong data analysis and presentation skills, relevant statistical and regulatory knowledge to plan and execute assay qualification and validation.
- Experience with PK and/or ADA assays beneficial, but not essential.
- Be proactive and independent with good communication skills and high level of attention to detail.
- Be a committed team player able to work well within small teams or individually as well as contribute to the wider group.
UK EEO:
Abzena is committed to promoting equal opportunities in employment. All our employees and any job applicants will receive equal treatment regardless of age, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief, sex or sexual orientation (“Protected Characteristics”).
