Associate Director, Clinical Pharmacology
CompanyAlnylam Pharmaceuticals
Location
Maidenhead, England, United Kingdom
Employment TypeFull-time
Posted At2/4/2026
UK Visa Sponsorship Analytics
Occupation TypeHealth services and public health managers and directors
Occupation Code Skill LevelHigher Skilled
Sponsorship Salary Threshold
£50,300
(£25.79 per hour)
Occupation rate applies
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Description
Overview
The Associate Director, Clinical Pharmacology supports a rapidly expanding clinical portfolio of RNAi therapeutics within the CNS franchise. This role provides clinical pharmacology expertise across clinical-stage programs, with a strong focus on pharmacokinetics (PK), pharmacodynamics (PD), and PK/PD analyses to inform clinical development and regulatory decision-making.
The position requires strong scientific expertise, critical thinking, and the ability to independently interpret and integrate complex clinical pharmacology data within a highly matrixed environment. The Associate Director partners closely with Research, Clinical Development, Bioanalytical, Regulatory, Project Management, and other R&D functions, contributing to clinical study design, data analysis, regulatory submissions, and scientific publications in support of advancing innovative RNAi therapies.
This is a virtual role based in The Netherlands or UK.
Key Responsibilities
The Associate Director, Clinical Pharmacology supports a rapidly expanding clinical portfolio of RNAi therapeutics within the CNS franchise. This role provides clinical pharmacology expertise across clinical-stage programs, with a strong focus on pharmacokinetics (PK), pharmacodynamics (PD), and PK/PD analyses to inform clinical development and regulatory decision-making.
The position requires strong scientific expertise, critical thinking, and the ability to independently interpret and integrate complex clinical pharmacology data within a highly matrixed environment. The Associate Director partners closely with Research, Clinical Development, Bioanalytical, Regulatory, Project Management, and other R&D functions, contributing to clinical study design, data analysis, regulatory submissions, and scientific publications in support of advancing innovative RNAi therapies.
This is a virtual role based in The Netherlands or UK.
Key Responsibilities
- Represent independently Clinical Pharmacology and provide clinical pharmacology support and guidance to clinical stage project teams.
- Lead the analysis, interpretation, integration and reporting of clinical pharmacology data
- Conduct PK and PK/PD analyses to guide clinical development decisions
- Provide clinical pharmacology input for regulatory submissions such as briefing documents, IND, CTA and NDA
- Prepare and input independently appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study Reports with respect to Clinical Pharmacology studies or data
- Closely partner with Research, Bioanalytical, Clinical, Regulatory, Project Management, and other R&D functions
- Preparation of abstracts and manuscripts for publications
- Ph.D. ( or Pharm.D.) in relevant field (i.e. Pharmacokinetics, Pharmacometrics, Clinical Pharmacology) with in depth experience in pharmaceutical/biotech industry
Join a company recognized for its innovation, open culture, and commitment to people. At Alnylam, you’ll work in an environment that values collaboration, purpose, and excellence — and be part of a team bringing groundbreaking RNAi therapies to patients in need.
Apply now to make a difference where science meets purpose.