Associate Principal Scientist (In Vitro DMPK)

CompanyPharmaron

LocationHoddesdon, England, United Kingdom

Posted At1/13/2026

UK Visa Sponsorship Analytics

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Occupation Type

Natural and social science professionals not elsewhere classified.

Occupation Code Skill LevelHigher Skilled

Sponsorship Salary Threshold

£41,700 (£21.38 per hour)

Standard minimum applies

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Description

Job Introduction

Position: Associate Principal Scientist (In Vitro DMPK)

Location: Hoddesdon

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit www.pharmaron.com.

About The Role

We are looking for an Associate Principal Scientist to join our In Vitro DMPK Assay group at our Hoddesdon site supporting Discovery ADME screening through to early development (e.g. studies associated with ICHM12).

As a subject matter expert, you will develop in vitro DMPK laboratory solutions to specific project requirements, ensuring appropriate experimental conditions are applied.

Key Responsibilities

Design, plan and optimize in vitro DMPK experimental plans to solve complex questions. Inherent in this is the requirement for appropriate original research for the purpose of contributing positively to this accountability.
Effectively lead and coordinate teams of multi-disciplinary and frequently, cross functional scientists, to deliver agreed project outputs.
Actively contribute to the knowledge and capability of the organisation through the guidance, training, mentoring and sharing of best practice with scientific colleagues in general, and with new and inexperienced staff in particular.
Lead, document and report/present results of all experiments in line with department practices and policies.
Act as a system owner of equipment and instrumentation, including supporting qualification activities.
Lead on the implementation and adoption of key internal business practices and applicable external regulations and adhere to all policies governing their business activities.
Work closely with other teams within Biosciences, in particular Bioanalysis colleagues, to ensure efficient and joint ways of working.
Support and positively contribute to departmental or site audits as directed by scientific supervisor / Line Manager as necessary.

Candidate Profile

An MSc or a BSc in a Biological Science, Chemistry or related subject with industrial experience working in a relevant role
Significant knowledge and experience of either application of ICHM12 guidelines, lab automation or high throughput discovery screening assays
Evidence of experience in successful application of DMPK skill sets to resolve project and assay issues
Broad experience in DMPK bench science and data manipulation, applying expert knowledge of a wide range of laboratory techniques and instrumentation to address customer needs
Working knowledge of LCMS/MS data interpretation
Ability to effectively contribute to multi-disciplinary scientific teams, enabling project progression
Experience in mentoring or coaching of junior staff
Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues and customers.
Excellent interpersonal skills with the ability to build strong working relationships with stakeholders and customers

Why Pharmaron?

Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

How to Apply:

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.