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AstraZeneca

Senior Scientist: Process Engineering

CompanyAstraZeneca
LocationMacclesfield, England, United Kingdom
Posted At3/18/2026

UK Visa Sponsorship Analytics

Analytics are greyed out due to low classification confidence (57.0%).
Occupation Type
Production and process engineers
Occupation Code Skill LevelHigher Skilled
Sponsorship Salary Threshold
£45,000 (£23.08 per hour)
Occupation rate applies

Above analytics are generated algorithmically based on job titles and may not always be the same as the company's job classification. You can also check detailed occupation eligibility, and salary criteria on our UK Visa Eligible Occupations & Salary Thresholds page.

Disclaimer: Hunt UK Visa Sponsors aggregates job listings from publicly available sources, such as search engines, to assist with your job hunting. We do not claim affiliation with AstraZeneca. For the most up-to-date job details, please visit the official website by clicking "Apply Now."

Description
Senior Scientist: Process Engineering – Global Product Development

Macclesfield, UK

About Pharmaceutical Technology & Development (PT&D) and Global Product Development (GPD)

PT&D is the bridge that turns brilliant science into real medicines, spanning the entire value chain—from early toxicology and clinical supplies to technology that enables robust commercial manufacture. Within PT&D, GPD leads the late stage design and development of drug products across a range of dosage forms. We develop the formulation, manufacturing process, and scientific understanding needed to scale, launch, and sustain new medicines. You’ll collaborate in highly multidisciplinary teams with engineers and pharmaceutical scientists to advance life-changing medicines for patients.

Come and join our AZ team where you will play a pivotal role in this exciting period of development!

We are seeking a Senior Scientist in Process Engineering with experience of parenteral product development (small molecule and new modalities, e.g. peptides) and / or oral solid dosage forms (tablets, capsules), and who will help grow our engineering capability within Global Product Development.

As a senior scientist you will play a key role in leading the process engineering aspects of projects in late-stage development spanning an exciting portfolio of projects spanning parenteral drug product development and oral solid dosage forms (including Continuous Direct Compression). You will be an important member of a multidisciplinary team, providing input to the overall product development, designing and delivering lab based work packages and driving the development and implementation of in silico tools to support and accelerate development.

Key Responsibilities

  • Lead engineering input for the design and development of robust manufacturing processes across parenteral and /or oral solid dosage forms.
  • Lab-based process development: plan and implement lab-scale experiments to facilitate project decisions
  • Shape the scientific and technical direction of product development activities through process understanding and control
  • Define and optimise critical process parameters (CPPs) and integrate them into control strategies.
  • Lead or contribute to technology transfer, risk assessment, process validation and scale‑up.
  • Apply modelling, simulation, digital twins and predictive tools to enhance process understanding.
  • Solve key technical challenges with direct impact on current project delivery.
  • Drive a culture of creativity, innovation and scientific excellence.
  • Cross-functional collaboration: Contribute to integrated drug product development plans within a multidisciplinary team.

  • Requirements

    • PhD or Degree in Chemical Engineering in addition to with relevant industrial experience
    • Hands‑on experience developing parenteral (aseptic/sterile injectables) and oral solid dose products, including formulation and process definition.
    • Experience leading in late‑stage product development, technology transfer, scale‑up and process validation.
    • Fundamental understanding of control strategy and risk management with experience designing and implementing end‑to‑end control strategies, performed formal risk assessments and defined monitoring plans and CAPAs.
    • Basic understanding of predictive science, artificial intelligence, modelling and simulation, with familiarity in AI/ML use cases, process simulation, and data pipelines.
    • Ability to communicate complex technical content clearly; partners effectively with Operations, and external CMOs; authors high‑quality technical reports and presents to governance.

    Desirables

    • Experience with a range of unit operations e.g. aseptic processing, continuous manufacturing, granulation, compression, coating.
  • Experience with regulatory authoring and defence.
  • Experience with CMOs/CROs and outsourced development.

  • In Office Requirement

    When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of five days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

    Competitive Salary And Benefits Package On Offer.

    The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.

    Date Posted

    17-Mar-2026

    Closing Date

    30-Mar-2026

    Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.