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Downstream Process Scientist
Not disclosed
Salary
Not disclosed by employer
£41,700
Going rate
Skilled Worker going rate
This role may qualify for a Skilled Worker visa
SOC 2119 is an eligible occupation, but we classified this role with low confidence (57% match). If the code is right — and HydRegen is a licensed sponsor — it should qualify, but double-check the occupation eligibility rules against the actual role.
About the role
Downstream Process Development & Analytical Chemist I Oxford I £40k - £50k (dependent on experience)
Are you an experienced analytical chemist with expertise in HPLC and a passion for developing scalable chemical purification processes? We're recruiting for a Downstream Process Development & Analytical Chemist to join an innovative biotechnology business developing sustainable solutions for the chemical manufacturing industry. This is a unique opportunity to take ownership of downstream process development and reaction analytics, using your expertise to optimise chemical manufacturing processes, troubleshoot analytical challenges and support the development of cutting-edge biocatalytic technologies.
The Role
This is a hands-on laboratory role where you'll become the subject matter expert for HPLC, taking ownership of method development, troubleshooting, instrument maintenance and routine analysis. Alongside this, you'll lead the development of downstream processing (DSP) strategies for small molecule chemical products produced through biomanufacturing. This role focuses on chemical purification and process development rather than protein purification, making it ideal for someone with experience in industrial chemistry or chemical process development.
Working closely with chemists and engineers, you'll generate robust analytical data, develop scalable purification processes and help translate laboratory research into commercially viable manufacturing solutions.
Key Responsibilities
- Act as the HPLC specialist, leading method development, troubleshooting, routine analysis, calibration and instrument maintenance.
- Develop and validate analytical methods using HPLC, alongside techniques such as NMR and UV-Vis.
- Design and optimise downstream processing routes for chemical products generated through biocatalytic manufacturing.
About You
We're looking for someone who can demonstrate:
- A degree in Chemistry, Analytical Chemistry or a related scientific discipline.
- At least three years' industrial experience in analytical chemistry.
- Extensive hands-on experience with HPLC, including method development, troubleshooting, maintenance and routine operation.
- Experience supporting reaction monitoring and analysing complex chemical reaction mixtures.
- Practical experience in downstream processing and purification of small molecule chemicals, ideally within biomanufacturing, chemical manufacturing or process chemistry environments.
- An understanding that downstream processing in this role relates to chemical manufacturing rather than protein purification.
- Excellent problem-solving, communication and collaboration skills.
Apply
If you're looking to apply your HPLC expertise and downstream processing experience in an innovative organisation developing sustainable technologies for the chemical manufacturing sector, we'd love to hear from you.
Katie Pink at Cranleigh STEM & Sustainability is the retained recruitment partner for all roles at Hydregen. Please direct any queries to Katie only.
This description is the source posting as it read when we added it. We are not affiliated with HydRegen, so check their own site for the current details.
Where this offer sits in the market
SOC 2119 · UK · ONS ASHE 2025 · ~36k in sampleSimilar sponsored roles
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About sponsorship for this role
Does this job guarantee visa sponsorship?
Not necessarily. HydRegen holds a sponsor licence, but sponsorship for a specific hire is always the employer's decision. Be upfront in your application that you'll require it.
What salary is needed for this role to be eligible?
The offer must clear both the general threshold and the SOC 2119 going rate of £41,700. New-entrant and shortage discounts can lower it.