Principal Research Associate, Clinical Biomarker Laboratory, Flow Cytometry

The Role

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.

This role is based in Oxford and offers the opportunity to be at the forefront of clinical immunology, applying advanced spectral flow cytometry technologies to generate critical data that informs clinical development decisions across multiple therapeutic areas. As part of the Clinical Flow Cytometry group, you will serve as a technical expert operating within a GCLP environment, supporting the development, validation, and execution of complex cell-based assays for clinical programs.

Working alongside a highly collaborative team of scientists, you will leverage high-parameter flow cytometry, functional immune profiling, and innovative analytical approaches to deliver high-quality clinical data. You will also have opportunities to engage with emerging digital technologies and Generative AI-enabled tools that support data interpretation, workflow optimization, documentation, and operational excellence across the clinical laboratory environment.

Here's What You'll Do

• Serve as a technical expert within the Clinical Flow Cytometry group, supporting clinical programs across multiple therapeutic areas through the generation of high-parameter flow cytometry data under GCLP guidelines.
• Execute clinical sample testing under GCLP requirements while maintaining the highest standards of quality, compliance, and data integrity.
• Set up and perform ex vivo assays, including ex vivo stimulation protocols for functional profiling of immune responses using validated assays on clinical trial samples.
• Perform high-parameter immunophenotyping on PBMC and whole blood samples utilizing advanced spectral flow cytometry platforms.
• Conduct PBMC isolation and cryopreservation from blood products in accordance with established procedures and quality standards.

Experience in assessing cell-mediated immunity through flow cytometry: ex vivo stimulation of PBMC and intracellular cytokine staining for functional profiling is highly desirable.

Experience working in a regulated environment (GCP, GLP, ISO standard) and within a clinical testing laboratory is highly desirable

Possess good computational skills, experienced with GraphPad Prism, R.

Up to date on best practices in flow cytometry and application to clinical trials

Demonstrated level of independence

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our global benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being with access to fitness, mindfulness, and mental health support
• Family building benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras
  
  

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office coll

aboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is committed to equal opportunity in employment and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at leavesandaccommodations@modernatx.com.